Biomedical Optics (Biophotonics)
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Biomedical
Optics





Biomedical optics at the LMTB comprises the development and improvement of optical methods for medical applications, biomedical research and biotechnology. Laser therapy originally played a central role, in the sense of a new minimal invasive therapy, in Laser Induced Thermo Therapy (LITT) which was developed at the LMTB, together with its therapy-related dosimetry. The natural progression of this technology is to be found in Photodynamic Therapy (PDT) and its dosimetry.

The study of tissue optics, which is an area of core expertise for the LMTB, enables an in-depth understanding of the light distribution in biological tissue. As a result it has become a key discipline in basic laser therapy. With the development of imaging and spectroscopic methods for diagnostic applications, the importance of tissue optics has increased and has led to many successful developments at the LMTB. This is due to the fact that diagnostic methods usually require the detection of substances in a strongly scattering biological environment. Blood sensors are a good example of a successful independent development at the LMTB which utilize an in-depth understanding of light distribution in a scattering medium.

Modern medicine, as we know it, is unthinkable without imaging methods. LMTB has been instrumental in advancing developments at organ level (colposcopy, intraoperative fluorescence imaging), at tissue level (mini confocal laser scanning microscope) and at the molecular level (molecular screening). A broad variety of molecular diagnostic and analytic methods developed at LMTB are based on spectroscopic methods. With the advent of molecular medicine and biotechnology, promoted by new developments in lasers and optoelectronics, the focus has now shifted at the LMTB in favor of molecular diagnostics and molecular imaging. The specific advantages afforded by optics can be exploited using wavelengths in the infrared, UV and visible range, thereby allowing very specific spectroscopic information to be detected and evaluated.


Contact person
Dr. Jürgen Helfmann